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Table 2 Overview of case studies on malaria among displaced populations in Africa

From: Improving diagnostics and surveillance of malaria among displaced people in Africa

Case Study Location

Population

Intervention

Key Outcomes

Authors

Sofala and Cabo Delgado, Mozambique

Displaced persons post-cyclone and violence

Surveillance activities, RDT administration

Identified a 4.5% malaria-positive rate among screened individuals; highlighted the need for combined diagnostic algorithms due to COVID-19 and malaria symptom overlap

Di Gennaro et al. 2022

Northern Zambia

Congolese refugee children

Surveillance data and hospital record analysis

Similar malaria prevalence in refugee settlements and high-burden areas; refugee children from transit centers had better outcomes than those from permanent settlements

Hauser et al. 2022

Eastern DRC, IDP camp

100 Febrile Children Under 5 years of age from the IDP camp

Active case detection of household contacts

Active case-finding was not efficient; symptom-based screening was suggested for identifying at-risk individuals

Hamze et al. 2016

Displacement camp, DRC

Children living in displacement camp

Cross-sectional surveys, RDTs

Higher prevalence of P. falciparum infection in camp children compared to nearby village; highlighted low bed net usage

Charchuk et al. 2016

General Hospitals in Ebonyi State, Nigeria

Patients with malaria symptoms

Comparison of diagnostics

Showed variability in diagnostic accuracy; recommended combined use of microscopy and RDT

Ugah et al. 2017

NorthWest,

Central African Republic (CAR)

Community through CHWs

Malaria RDTs and ACT treatment

High positivity rate; effective treatment with ACT for positive cases

Ruckstuhl et al. 2017

Ardamata IDP camp, Sudan

Patients with suspected malaria

Nested PCR for malaria detection

High malaria prevalence; highlighted gender as a risk factor

Eshag et al. 2020

Non-endemic countries

Suspected malaria in travellers, migrants, refugees

Novel FRET-qPCR diagnostic

Achieved high accuracy in species identification; suggested for routine clinical use

Schneider et al. 2021

South Sudan

Refugees, returnees, internally displaced people

Implementation of WHO-recommended malaria control interventions per the National Malaria Strategic Plan

Despite challenges, and progress in implementing malaria control interventions; the need for enhanced coordination, infrastructure, and resource allocation highlighted

Pasquale et al., 2013

North Wollo zone, Ethiopia

Patients, pregnant women, elders, community and religious leaders, health professionals

Use of traditional medicines, medications from unaffected areas, home-to-home healthcare

The conflict led to a breakdown in the health system, affecting the provision and utilization of health services, including those for malaria. Coping strategies were developed in response

Arage et al., 2023

Eight countries in sub-Saharan Africa

Cameroon, DRC, Ghana, Nigeria, Senegal, Sierra Leone, Tanzania, and Uganda)

Community health workers, health center managers, parents of children receiving chemoprevention, national decision-makers

SMC and IPTi

SMC and IPTi are largely accepted but face challenges like children's absenteeism, parents' reluctance, access to water, and staff turnover. Identified drivers and barriers to acceptance

Audibert & Tchouatieu, 2021

  1. Abbreviations: DRC Democratic Republic of Congo, SMC Seasonal Malaria Chemoprevention, RDT Rapid Diagnostic Tests, PCR Polymerase Chain Reaction, IDP Internally Displaced Persons